Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0317834
PubChem CID
Molecular Formula
C14H11N3S
Molecular Weight
253.33 g/mol
Synonyms/Alias
[N-phenyl-4-(pyridin-2-yl)thiazol-2-amine; CHEMBL490592; 315702-76-2; pyridyl-anilino-thiazole; CBMicro_027711; Phenyl-(4-pyridin-2-yl-thiazol-2-yl)-amine; Oprea1_609534; MLS000523459; cid_873000; SCH...
InChI Key
VZHGZKUEVAANEJ-UHFFFAOYSA-N
InChI
InChI=1S/C14H11N3S/c1-2-6-11(7-3-1)16-14-17-13(10-18-14)12-8-4-5-9-15-12/h1-10H,(H,16,17)
IUPAC Name
N-phenyl-4-pyridin-2-yl-1,3-thiazol-2-amine
CAS Number
315702-87-5

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

29 31 0 0 0 0 0 0 0 0999 V2000
-5.6621 0.1618 -0.0386 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.7752 -0.3635 0.9048 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.4058 -0.098...

Experimental Data

Activity Data

Target Ion Channel
Small conductance calcium activated potassium channel protein 3
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: >30000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
Not mention
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
18
Rotatable Bonds
3
logP
3.9487
Complexity
75.0697
TPSA (Ų)
37.81
H-Bond Donors
1
H-Bond Acceptors
4
Ring Count
3
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